ProSci

NCAPG Antibody

Product Code:
 
PSI-60-325
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in CEM cell line lysates (35ug/lane).
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Western blot analysis in CEM cell line lysates (35ug/lane).

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PSI-60-325-400ul400ul£626.00
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Further Information

Additional Names:
Condensin complex subunit 3, Chromosome-associated protein G, Condensin subunit CAP-G, hCAP-G, Melanoma antigen NY-MEL-3, Non-SMC condensin I complex subunit G, XCAP-G homolog, NCAPG, CAPG, NYMEL3
Application Note:
For WB starting dilution is: 1:1000
Background:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Background References:
  • Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
  • Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
  • Murphy, L.A., et al. Biochem. Biophys. Res. Commun. 377(3):1007-1011(2008)
  • Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NCAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the N-terminal region of human NCAPG.
NCBI Gene ID #:
64151
NCBI Official Name:
Condensin complex subunit 3
NCBI Official Symbol:
NCAPG
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
114 kDa
Protein Accession #:
Q9BPX3
Protein GI Number:
30172941
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Immunology,Signal Transduction
Swissprot #:
Q9BPX3
User NOte:
Optimal dilutions for each application to be determined by the researcher.