Further Information
Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15
For WB starting dilution is: 1:1000
This gene encodes an evolutionarily conserved protein
associated with cell apoptosis. The protein interacts with the
serine/threonine protein kinase MST4 to modulate the extracellular
signal-regulated kinase (ERK) pathway. It also interacts with and
is phosphoryated by serine/threonine kinase 25, and is thought to
function in a signaling pathway essential for vascular developent.
Mutations in this gene are one cause of cerebral cavernous
malformations, which are vascular malformations that cause seizures
and cerebral hemorrhages. Multiple alternatively spliced variants,
encoding the same protein, have been identified. [provided by
RefSeq].
- Lauenborg, B., et al. APMIS 118(10):719-728(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Ding, J., et al. Biochem. Biophys. Res. Commun. 399(4):587-592(2010)
- Zheng, X., et al. J. Clin. Invest. 120(8):2795-2804(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Rat, Xenopus
This PDCD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human PDCD10.
11235
Programmed cell death protein 10
PDCD10
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Q9BUL8
74733232
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Cell Cycle,Neuroscience,Signal Transduction
Q9BUL8
Optimal dilutions for each application to be determined by the researcher.