ProSci

FBXO4 Antibody

Product Code:
 
PSI-63-878
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of FBXO4 Antibody in Y79 cell line lysates (35ug/lane)
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Western blot analysis of FBXO4 Antibody in Y79 cell line lysates (35ug/lane)

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PSI-63-878-400ul400ul£626.00
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Further Information

Additional Names:
F-box only protein 4, FBXO4, FBX4
Application Note:
For WB starting dilution is: 1:1000
Background:
FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.
Background References:
  • Zeng,Z., et.al., Dev. Cell 18 (2), 214-225 (2010)
  • Barbash,O., et.al., Cancer Cell 14 (1), 68-78 (2008)
  • Sugiyama,N., et.al., Mol. Cell Proteomics(6), 1103-1109 (2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This FBXO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-251 amino acids from the Central region of human FBXO4.
NCBI Gene ID #:
26272
NCBI Official Name:
F-box only protein 4
NCBI Official Symbol:
FBXO4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q9UKT5
Protein GI Number:
60416426
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9UKT5
User NOte:
Optimal dilutions for each application to be determined by the researcher.