Further Information
S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, p19A, Organ of Corti protein 2, OCP-2, Organ of Corti protein II, OCP-II, RNA polymerase II elongation factor-like protein, SIII, Transcription elongation factor B polypeptide 1-like, p19skp1, SKP1, EMC19, OCP2, SKP1A, TCEB1L
For WB starting dilution is: 1:1000
SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.
- Wu, G., et al., Mol. Cell 11(6):1445-1456 (2003).
- Piva, R., et al., Mol. Cell. Biol. 22(23):8375-8387 (2002).
- Matsuzawa, S.I., et al., Mol. Cell 7(5):915-926 (2001).
- Schulman, B.A., et al., Nature 408(6810):381-386 (2000).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat, Xenopus
This SKP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human SKP1.
6500
S-phase kinase-associated protein 1
SKP1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
P63208
52783797
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Cell Cycle
P63208
Optimal dilutions for each application to be determined by the researcher.