ProSci

UBP46 Antibody

Product Code:
 
PSI-57-525
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

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PSI-57-525-400ul400ul£626.00
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Further Information

Additional Names:
Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46, USP46
Application Note:
For WB starting dilution is: 1:1000
Background:
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
Background References:
  • Kushima, I., et al. J. Hum. Genet. 55(3):133-136(2010)
  • Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)
  • Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009)
  • Quesada, V., et al. Biochem. Biophys. Res. Commun. 314(1):54-62(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse
Immunogen:
This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human UBP46.
NCBI Gene ID #:
64854
NCBI Official Name:
Ubiquitin carboxyl-terminal hydrolase 46
NCBI Official Symbol:
USP46
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P62068
Protein GI Number:
49065850
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P62068
User NOte:
Optimal dilutions for each application to be determined by the researcher.