Further Information
Retinoic acid receptor beta, RAR-beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, RARB, HAP, NR1B2
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
This gene encodes retinoic acid receptor beta, a member of
the thyroid-steroid hormone receptor superfamily of nuclear
transcriptional regulators. This receptor localizes to the
cytoplasm and to subnuclear compartments. It binds retinoic acid,
the biologically active form of vitamin A which mediates cellular
signalling in embryonic morphogenesis, cell growth and
differentiation. It is thought that this protein limits growth of
many cell types by regulating gene expression. The gene was first
identified in a hepatocellular carcinoma where it flanks a
hepatitis B virus integration site. The gene expresses at least two
transcript variants; one additional transcript has been described,
but its full length nature has not been determined. [provided by
RefSeq].
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Miladi-Abdennadher, I., et al. Tumour Biol. 31(5):503-511(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
This RARB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human RARB.
5915
Retinoic acid receptor beta
RARB
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
P10826
17380507
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Signal Transduction
P10826
Optimal dilutions for each application to be determined by the researcher.