ProSci

GRAP2 Antibody

Product Code:
 
PSI-57-955
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

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PSI-57-955-400ul400ul£626.00
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Further Information

Additional Names:
GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, P38, Protein GADS, SH3-SH2-SH3 adapter Mona, GRAP2, GADS, GRB2L, GRID
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human GRAP2.
NCBI Gene ID #:
9402
NCBI Official Name:
GRB2-related adapter protein 2
NCBI Official Symbol:
GRAP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
O75791
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
O75791
User NOte:
Optimal dilutions for each application to be determined by the researcher.