ProSci

ABCC4 Antibody

Product Code:
 
PSI-62-908
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-ABCC4 Antibody in CEM cell line lysates (35ug/lane)
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Western blot analysis of anti-ABCC4 Antibody in CEM cell line lysates (35ug/lane)

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PSI-62-908-400ul400ul£626.00
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Further Information

Additional Names:
Multidrug resistance-associated protein 4, ATP-binding cassette sub-family C member 4, MRP/cMOAT-related ABC transporter, Multi-specific organic anion transporter B, MOAT-B, ABCC4, MRP4
Application Note:
For WB starting dilution is: 1:1000
Background:
ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
Background References:
  • Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747(1998)
  • Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004(2002)
  • Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547(1997)
  • Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1145 amino acids from the C-terminal region of human ABCC4.
NCBI Gene ID #:
10257
NCBI Official Name:
Multidrug resistance-associated protein 4
NCBI Official Symbol:
ABCC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
150 kDa
Protein Accession #:
O15439
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Signal Transduction
Swissprot #:
O15439
User NOte:
Optimal dilutions for each application to be determined by the researcher.