ProSci

MTA3 Antibody

Product Code:
 
PSI-58-521
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Ramos cell line lysates (35ug/lane).
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Western blot analysis in Ramos cell line lysates (35ug/lane).

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PSI-58-521-400ul400ul£626.00
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Further Information

Additional Names:
Metastasis-associated protein MTA3, MTA3, KIAA1266
Application Note:
For WB starting dilution is: 1:1000
Background:
MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
Background References:
  • Bruning, A., et al. Histochem. Cell Biol. 132(1):33-38(2009)
  • Lasky-Su, J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (8), 1345-1354 (2008) :
  • Zhang, H., et al. Genes Dev. 20(21):2943-2948(2006)
  • Yu, J.C., et al. J. Biomed. Sci. 13(3):419-432(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This MTA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-587 amino acids from the C-terminal region of human MTA3.
NCBI Gene ID #:
57504
NCBI Official Name:
Metastasis-associated protein MTA3
NCBI Official Symbol:
MTA3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q9BTC8
Protein GI Number:
29840798
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q9BTC8
User NOte:
Optimal dilutions for each application to be determined by the researcher.