Further Information
Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, SCP-2, Sterol carrier protein X, SCP-X, SCP2
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
This gene encodes two proteins: sterol carrier protein X
(SCPx) and sterol carrier protein 2 (SCP2), as a result of
transcription initiation from 2 independently regulated promoters.
The transcript initiated from the proximal promoter encodes the
longer SCPx protein, and the transcript initiated from the distal
promoter encodes the shorter SCP2 protein, with the 2 proteins
sharing a common C-terminus. Evidence suggests that the SCPx
protein is a peroxisome-associated thiolase that is involved in the
oxidation of branched chain fatty acids, while the SCP2 protein is
thought to be an intracellular lipid transfer protein. This gene is
highly expressed in organs involved in lipid metabolism, and may
play a role in Zellweger syndrome, in which cells are deficient in
peroxisomes and have impaired bile acid synthesis. Alternative
splicing of this gene produces multiple transcript variants, some
encoding different isoforms.
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Rikova, K., et al. Cell 131(6):1190-1203(2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human SCP2.
6342
Non-specific lipid-transfer protein
SCP2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
P22307
2507456
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Signal Transduction
P22307
Optimal dilutions for each application to be determined by the researcher.