ProSci

FDFT1 Antibody

Product Code:
 
PSI-57-820
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis of FDFT1 using rabbit polyclonal FDFT1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDFT1 gene.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis of FDFT1 using rabbit polyclonal FDFT1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDFT1 gene.

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PSI-57-820-400ul400ul£626.00
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Further Information

Additional Names:
Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Background References:
  • Chalasani, N., et al. Gastroenterology 139(5):1567-1576(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Kovanen, L., et al. Alcohol Alcohol. 45(4):303-311(2010)
  • Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.
NCBI Gene ID #:
2222
NCBI Official Name:
Squalene synthase
NCBI Official Symbol:
FDFT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P37268
Protein GI Number:
585126
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience
Swissprot #:
P37268
User NOte:
Optimal dilutions for each application to be determined by the researcher.