ProSci

OS9 Antibody

Product Code:
 
PSI-59-053
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in U937 cell line lysates (35ug/lane).
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Western blot analysis in U937 cell line lysates (35ug/lane).

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PSI-59-053-400ul400ul£626.00
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Further Information

Additional Names:
Protein OS-9, Amplified in osteosarcoma 9, OS9
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Background References:
  • Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
  • Mikami, K., et al. Glycobiology 20(3):310-321(2010)
  • Hosokawa, N., et al. J. Biol. Chem. 284(25):17061-17068(2009)
  • Jansen, B.J., et al. Mol. Immunol. 46(4):505-515(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This OS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of human OS9.
NCBI Gene ID #:
10956
NCBI Official Name:
Protein OS-9
NCBI Official Symbol:
OS9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q13438
Protein GI Number:
3024310
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
Q13438
User NOte:
Optimal dilutions for each application to be determined by the researcher.