ProSci

ADAM23 Antibody

Product Code:
 
PSI-58-528
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A2058 cell line lysates (35ug/lane).
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Western blot analysis in A2058 cell line lysates (35ug/lane).

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PSI-58-528-400ul400ul£626.00
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Further Information

Additional Names:
Disintegrin and metalloproteinase domain-containing protein 23, ADAM 23, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3, MDC-3, ADAM23, MDC3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.
Background References:
  • Pan, Q., et al. Biochem. Biophys. Res. Commun. 401(2):306-312(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Ferreira, M.A., et al. Allergy 64(11):1623-1628(2009)
  • Costa, M.D., et al. Neurosci. Lett. 461(1):16-20(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ADAM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 803-831 amino acids from the C-terminal region of human ADAM23.
NCBI Gene ID #:
8745
NCBI Official Name:
Disintegrin and metalloproteinase domain-containing protein 23
NCBI Official Symbol:
ADAM23
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
O75077
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
O75077
User NOte:
Optimal dilutions for each application to be determined by the researcher.