ProSci

GPC4 Antibody

Product Code:
 
PSI-61-505
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of GPC4 Antibody in K562 cell line lysates (35ug/lane)
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Western blot analysis of GPC4 Antibody in 293 cell line lysates (35ug/lane)
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Western blot analysis of GPC4 Antibody in K562 cell line lysates (35ug/lane)
Western blot analysis of GPC4 Antibody in 293 cell line lysates (35ug/lane)

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PSI-61-505-400ul400ul£626.00
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Further Information

Additional Names:
Glypican-4, K-glypican, Secreted glypican-4, GPC4
Application Note:
For WB starting dilution is: 1:1000
Background:
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
Background References:
  • Karumanchi,S.A., Mol. Cell(4), 811-822 (2001)
  • Hagihara,K., Dev. Dyn. 219 (3), 353-367 (2000)
  • Veugelers,M., Hum. Mol. Genet.(9), 1321-1328 (2000)
  • Veugelers,M., Genomics 53 (1), 1-11 (1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the Central region of human GPC4.
NCBI Gene ID #:
2239
NCBI Official Name:
Glypican-4
NCBI Official Symbol:
GPC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
O75487
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Neuroscience,Signal Transduction
Swissprot #:
O75487
User NOte:
Optimal dilutions for each application to be determined by the researcher.