Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR-related orphan receptor C, Retinoid-related orphan receptor-gamma, RORC, NR1F3, RORG, RZRG
For WB starting dilution is: 1:1000
The protein encoded by this gene is a DNA-binding
transcription factor and is a member of the NR1 subfamily of
nuclear hormone receptors. The specific functions of this protein
are not known; however, studies of a similar gene in mice have
shown that this gene may be essential for lymphoid organogenesis
and may play an important regulatory role in thymopoiesis. In
addition, studies in mice suggest that the protein encoded by this
gene may inhibit the expression of Fas ligand and IL2. Two
transcript variants encoding different isoforms have been found for
this gene.
- Wang, Y., et al. Biochim. Biophys. Acta 1801(8):917-923(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Burgler, S., et al. J. Immunol. 184(11):6161-6169(2010)
- Jin, L., et al. Mol. Endocrinol. 24(5):923-929(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This RORC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human RORC.
6097
Nuclear receptor ROR-gamma
RORC
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
P51449
49066040
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Neuroscience,Signal Transduction
P51449
Optimal dilutions for each application to be determined by the researcher.