ProSci

KIT Antibody

Product Code:
 
PSI-60-282
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KIT antibody detected the KIT protein (arrow).
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KIT antibody detected the KIT protein (arrow).

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PSI-60-282-400ul400ul£626.00
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Further Information

Additional Names:
Mast/stem cell growth factor receptor Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117, Kit, Sl
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Molderings, G.J., et al. Immunogenetics 62 (11-12), 721-727 (2010) :
  • Cheng, M., et al. Circ. Res. 107(9):1083-1093(2010)
  • Chi, P., et al. Nature 467(7317):849-853(2010)
  • Rossi, S., et al. Am. J. Surg. Pathol. 34(10):1480-1491(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Pig
Immunogen:
This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-836 amino acids from the C-terminal region of human KIT.
NCBI Gene ID #:
16590
NCBI Official Name:
Mast/stem cell growth factor receptor Kit
NCBI Official Symbol:
Kit
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
109 kDa
Protein Accession #:
P05532
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Neuroscience,Signal Transduction
Swissprot #:
P05532
User NOte:
Optimal dilutions for each application to be determined by the researcher.