ProSci

ITGB1 Antibody

Product Code:
 
PSI-60-417
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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PSI-60-417-400ul400ul£626.00
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Further Information

Additional Names:
Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12
Application Note:
For WB starting dilution is: 1:1000
Background:
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Background References:
  • Martchenko, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15583-15588(2010) Caicedo-Carvajal, C.E., et al. PLoS ONE(7), E11830 (2010)Rikova, K., et al. Cell 131(6):1190-1203(2007) Seales, E.C., et al. J. Biol. Chem. 280(45):37610-37615(2005) Armulik, A. Front. Biosci. 7, D219-D227 (2002) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Chicken, Xenopus, Bovine
Immunogen:
This ITGB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-785 amino acids from the C-terminal region of human ITGB1.
NCBI Gene ID #:
3688
NCBI Official Name:
Integrin beta-1
NCBI Official Symbol:
ITGB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
P05556
Protein GI Number:
218563324
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Neuroscience,Signal Transduction
Swissprot #:
P05556
User NOte:
Optimal dilutions for each application to be determined by the researcher.