Further Information
High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, Trk-A, gp140trk, p140-TrkA, NTRK1, MTC, TRK, TRKA
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
- Tokusashi, Y., et al., Int. J. Cancer 114(1):39-45 (2005).
- Schulte, J.H., et al., Oncogene 24(1):165-177 (2005).
- Frattini, M., et al., Oncogene 23(44):7436-7440 (2004).
- Tacconelli, A., et al., Cancer Cell 6(4):347-360 (2004).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Chicken, Rat
This TRKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human TRKA.
4914
High affinity nerve growth factor receptor
NTRK1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
P04629
94730402
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Cell Cycle,Neuroscience,Signal Transduction
P04629
Optimal dilutions for each application to be determined by the researcher.