ProSci

MLF1IP Antibody

Product Code:
 
PSI-59-196
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in WiDr cell line lysates (35ug/lane).
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Western blot analysis in WiDr cell line lysates (35ug/lane).

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PSI-59-196-400ul400ul£626.00
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Further Information

Additional Names:
Centromere protein U, CENP-U, Centromere protein of 50 kDa, CENP-50, Interphase centromere complex protein 24, KSHV latent nuclear antigen-interacting protein 1, MLF1-interacting protein, Polo-box-interacting protein 1, CENPU, ICEN24, KLIP1, MLF1IP, PBIP1
Application Note:
For WB starting dilution is: 1:1000
Background:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).
Background References:
  • Suzuki, H., et al. Anticancer Res. 27 (3B), 1423-1430 (2007) :
  • Kang, Y.H., et al. Mol. Cell 24(3):409-422(2006)
  • Izuta, H., et al. Genes Cells 11(6):673-684(2006)
  • Okada, M., et al. Nat. Cell Biol. 8(5):446-457(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MLF1IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human MLF1IP.
NCBI Gene ID #:
79682
NCBI Official Name:
Centromere protein U
NCBI Official Symbol:
CENPU
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q71F23
Protein GI Number:
74712714
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,
Swissprot #:
Q71F23
User NOte:
Optimal dilutions for each application to be determined by the researcher.