Chemodex

Caroverin

Product Code:
 
CDX-C0260
Product Group:
 
Other Biochemicals
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short Term: +20°C. Long Term: +4°C
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Chemical Structure

Chemical Structure

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CDX-C0260-M01010 mg£108.00
Quantity:
CDX-C0260-M05050 mg£401.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
1-[2-(Diethylamino)ethyl]-3-(p-methoxybenzyl)-2-quinoxalone; Spadon; Spasmium
Appearance:
White or slightly yellow, fine powder.
CAS:
23465-76-1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C22H27N3O2/c1-4-24(5-2)14-15-25-21-9-7-6-8-19(21)23-20(22(25)26)16-17-10-12-18(27-3)13-11-17/h6-13H,4-5,14-16H2,1-3H3
InChiKey:
MSPRUJDUTKRMLM-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 23465-76-1. Formula: C22H27N3O2. MW: 365.47. Synthetic. Quinoxaline compound, originally developed as a spasmolytic drug. Acts as an N-type calcium channel blocker, competitive AMPA receptor antagonist, and non-competitive NMDA receptor antagonist. Antioxidant agent through partial prevention of the formation and the highly active scavenging of hydroxyl radicals. Used to treat inner ear diseases such as tinnitus. Shown to inhibit tumor-promoting factors and potentially useful as a chemotherapeutic agent.
MDL:
MFCD00865257
Molecular Formula:
C22H27N3O2
Molecular Weight:
365.47
Package Type:
Vial
Precautions:
P264, P270, P301, P312, P330, P501
Product Description:
Quinoxaline compound, originally developed as a spasmolytic drug. Acts as an N-type calcium channel blocker, competitive AMPA receptor antagonist, and non-competitive NMDA receptor antagonist. Antioxidant agent through partial prevention of the formation and the highly active scavenging of hydroxyl radicals. Used to treat inner ear diseases such as tinnitus. Shown to inhibit tumor-promoting factors and potentially useful as a chemotherapeutic agent.
Purity:
>99% (HPLC)
Signal word:
Warning
SMILES:
O=C1N(CCN(CC)CC)C2=C(C=CC=C2)N=C1CC3=CC=C(OC)C=C3
Solubility Chemicals:
Soluble in DMSO (10 mg/ml). Insolube in water.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

References

(1) Y. Ishida, et al. Br. J. Pharmacol. 71, 343 (1980) | (2) B. Saletu, et al.; Arzneimittelforsch. 45, 217 (1995) | (3) D.M. Denk, et al.; Acta Otolaryngol. 117, 825 (1997) | (4) H. Nohl, et al.; Biofactors 19, 79 (2003) | (5) G. Haymerle, et al.; Eur. Arch. Otorhinolaryngol. 272, 3451 (2015)