Diaclone

Anti-Human CD18 Monoclonal Antibody, Unconjugated Clone MEM48

Product Code:
 
852.543.020
Product Group:
 
Primary Antibodies
Supplier:
 
Diaclone
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MEM48
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
 
Stable at +2-8°C for 12 months For longer storage, freeze aliquots
 

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852.543.020200 tests/2ml£311.00
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Further Information

Antigen:
CD18
Antigen Synonyms:
Integrin b 2
Conjugate:
Purified
Format:
Phosphate-buffered saline with 1% BSA and 0.09% sodium azide
Hybridoma:
Sp 2/0 - Ag 14 myeloma cell line
Immunisation:
Leucocytes from an LGL - type leukaemia
Reactivity:
Human
Research Area:
Cell Adhesion,CD Markers
Specificity:
Recognizes the CD18 molecule, a 95 kDa integrin molecule (β2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins.
Working Dilution:
Use 10 µl to label 106 cells or 100 µl of whole blood

References

  1. Bazil, V. et al., Fol. Biol. (Prague) 36 (1990). Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.. https://www.ncbi.nlm.nih.gov/pubmed/1971601
  2. Larson, R. S. & Springer T. A. Immunol Rev. 114, 181-217 (1990). Structure and function of leukocyte integrins.. https://www.ncbi.nlm.nih.gov/pubmed/2196220
  3. Stefanova I & Horejsi V. J. Immunol 5 1587-1592 (1991). Association of the CD59 and CD55 cell surface glycoproteins with other membrane molecules.. https://www.ncbi.nlm.nih.gov/pubmed/1715364