Diaclone

Anti-Human CD262 Monoclonal Antibody, Unconjugated Clone B-K29

Product Code:
 
854.863.020
Product Group:
 
Primary Antibodies
Supplier:
 
Diaclone
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
B-K29
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
Stable at +2-8°C for 12 months. For longer storage freeze aliquots
 

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854.863.020200 tests/2ml£214.00
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Further Information

Antigen:
TRAIL R2 / DR5
Antigen Synonyms:
DR5, TRAIL R2
Conjugate:
Purified
Format:
Phosphate-buffered saline with 1% BSA and 0.09% sodium azide
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TRAIL R2/Fc chimera
Reactivity:
Human
Research Area:
Apoptosis,CD Markers
Specificity:
Recognises a 42-46 kDa protein
Working Dilution:
Use 10 µl to label 106 cells or 100 µl of whole blood
Workshop:
VIII

References

  1. Merino, D. et al., Mol Cell Biol.,2005; 26(19): 7046-55.. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.. https://www.ncbi.nlm.nih.gov/pubmed/16980609
  2. Sirtl, S. et al.,Oncogene. 2018 Jul;37(30):4122-4136.. Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors.. https://www.ncbi.nlm.nih.gov/pubmed/29706657
  3. Ueda, R. et al., PNAS,2009; 0811817106.. Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.. https://www.ncbi.nlm.nih.gov/pubmed/19520829