AdipoGen Life Sciences

GSK429286A

Product Code:
 
SYN-1071
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
1 / 1
Chemical Structure
❮❯

Chemical Structure

No additional charges, what you see is what you pay! *

CodeSizePrice
SYN-1071-M100100 mgEnquire
Quantity:
SYN-1071-M0011 mg£115.00
Quantity:
SYN-1071-M0055 mg£192.00
Quantity:
SYN-1071-M01010 mg£279.00
Quantity:
SYN-1071-M05050 mg£789.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Related Products
  • Show All

Further Information

Alternate Names/Synonyms:
GSK-429286A; RHO-15
Appearance:
Solid.
CAS:
864082-47-3
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C21H16F4N4O2/c1-10-19(20(31)28-17-6-12-9-26-29-16(12)8-15(17)22)14(7-18(30)27-10)11-2-4-13(5-3-11)21(23,24)25/h2-6,8-9,14H,7H2,1H3,(H,26,29)(H,27,30)(H,28,31)
InChiKey:
OLIIUAHHAZEXEX-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 864082-47-3. Formula: C21H16F4N4O2. MW: 432.4. GSK429286A is a potent and selective inhibitor of Rho-associated kinase (ROCK1), with an IC(50) of 14nM. It is orally available and has been shown to dramatically reduce mean arterial pressure in spontaneously hypertensive rats.
Molecular Formula:
C21H16F4N4O2
Molecular Weight:
432.4
Package Type:
Plastic Vial
Product Description:
GSK429286A is a potent and selective inhibitor of Rho-associated kinase (ROCK1), with an IC(50) of 14nM. It is orally available and has been shown to dramatically reduce mean arterial pressure in spontaneously hypertensive rats.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease: R.J. Nichols, et al.; Biochem. J. 424, 47 (2009)