Storage:
Short Term: +4°C, Long Term: +4°C
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This product comes from:
Switzerland.
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7-10 working days.
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Further Information
Alternate Names/Synonyms:
(S)-4-Methyl-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride; H1152
Solid.
871543-07-6
32160000
liquid
H303, H317, H333
InChI=1S/C16H21N3O2S.2ClH/c1-12-9-18-11-14-5-3-6-15(16(12)14)22(20,21)19-8-4-7-17-10-13(19)2;;/h3,5-6,9,11,13,17H,4,7-8,10H2,1-2H3;2*1H/t13-;;/m0./s1
BFOPDSJOLUQULZ-GXKRWWSZSA-N
Chemical. CAS: 871543-07-6. Formula: C16H21N3O2S . 2HCl. MW: 319.4 . 72.9. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling, smooth muscle contraction and neuronal development.
C16H21N3O2S . 2HCl
319.4 . 72.9
Plastic Vial
H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling, smooth muscle contraction and neuronal development.
>95%
Warning
Soluble in DMSO.
Non-hazardous
Protein Kinase Modulators
12352200
Stable for at least 2 years after receipt when stored at -20°C.