AdipoGen Life Sciences

MK-2206 dihydrochloride

Product Code:
 
SYN-1162
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
1 / 1
Chemical Structure

Chemical Structure

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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
MK2206
Appearance:
Solid.
CAS:
1032350-13-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C25H21N5O.2ClH/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31;;/h1-3,5-11,14-15H,4,12-13,26H2,(H,29,31);2*1H
InChiKey:
HWUHTJIKQZZBRA-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1032350-13-2. Formula: C25H21N5O . 2HCl. MW: 407.5 . 72.9. MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC(50) of 8nM, 12nM and 65nM, respectively.
Molecular Formula:
C25H21N5O . 2HCl
Molecular Weight:
407.5 . 72.9
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC(50) of 8nM, 12nM and 65nM, respectively.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Selectively nonselective kinase inhibition: striking the right balance: R. Morphy; J. Med. Chem. 53, 1413 (2010)