AdipoGen Life Sciences

PF-04217903

Product Code:
 
SYN-1060
Product Group:
 
Inhibitors and Activators
Regulatory Status:
 
RUO
Shipping:
 
-20°C
1 / 1
Chemical Structure
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Chemical Structure

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Further Information

Alternate Names/Synonyms:
PF04217903
Appearance:
Solid.
CAS:
956905-27-4
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2
InChiKey:
PDMUGYOXRHVNMO-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 956905-27-4. Formula: C19H16N8O. MW: 372.4. PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Molecular Formula:
C19H16N8O
Molecular Weight:
372.4
Package Type:
Plastic Vial
Product Description:
PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitor: H.Y. Zou, et al.; Mol. Cancer Ther. 11, 1036 (2012)