Thrombopoietin Recombinant Protein

ProSci
Product Code: PSI-92-493
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-92-493-0.05mg0.05mg£838.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Further Information

Additional Names:
Thrombopoietin, C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Myeloproliferative leukemia virus oncogene ligand, THPO, TPO
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl,pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
N, C-6 His tag
NCBI Gene ID #:
7066
NCBI Official Name:
thrombopoietin
NCBI Official Symbol:
THPO
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
37.3 kD
Protein Accession #:
P40225
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P40225