ProSci

Legumain Recombinant Protein

Product Code:
 
PSI-91-342
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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CodeSizePrice
PSI-91-342-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Legumain, Asparaginyl Endopeptidase, Protease Cysteine 1, LGMN, PRSC1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Legumain is a lysosomal cysteine protease which is a member of the peptidase C13 family. Though it is found in many tissues, it is highly expressed in the kidney, heart, and placenta. Legumain has a strict specificity for hydrolysis of asparaginyl bonds and can also cleave aspartyl bonds slowly, especially under acidic conditions. Over-expression Legumain in tumors is significant for invasion and metastasis. In addition, Legumain may be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system and negative regulation of neuron apoptosis.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
5641
NCBI Official Name:
legumain
NCBI Official Symbol:
LGMN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
48.72 kD
Protein Accession #:
Q99538
Protein GI Number:
530363504
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q99538

Documents