Further Information
TGF-beta-1, CED, DPD1, TGFB, TGF-b1, TGFB1, CEDLAP, latency-associated peptide, TGFbeta, TGF-beta 1 protein, transforming growth factor beta-1
This recombinant protein can be used for biological assays. For research use only.
Transforming growth factor beta 1 (TGF beta 1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF- beta 1, TGF- beta 2 and TGF- beta 3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF- beta receptor type II (T beta R-II), and a TGF- beta receptor type I (T beta R-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF- beta expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Lyophilized from a 0.2 um filtered solution of 4 mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Tag Free
21803
transforming growth factor, beta 1
Tgfb1
Mus musculus
Lyophilized
Predicted Molecular Weight:
12.8 kD
P04202
767957252
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Human Cells
P04202