ProSci

CD137 Antibody

Product Code:
 
PSI-36-216
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-36-216-100ug100ug£524.00
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Further Information

Additional Names:
4-1BB; TNFRSF9
Application Note:
Flow Cytometry: (1:500-1:1,000). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 with 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Background:
CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human CD137.
NCBI Gene ID #:
3604
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 9
NCBI Official Symbol:
TNFRSF9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
728738
Protein GI Number:
Q07011
Research Area:
Cancer,Immunology
SPECIFICITY:
Recognizes human CD137. Detects a band of ~29kDa by Western blot. Does not cross-react with mouse CD137.
Swissprot #:
Q07011
User NOte:
Optimal dilutions for each application to be determined by the researcher.