ProSci

Jagged-1 Antibody [J1G53-3] (FITC)

Product Code:
 
PSI-36-052
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
J1G53-3
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C.
 

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PSI-36-052-50ug50ug£524.00
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Further Information

Additional Names:
Protein Jagged-1; CD339; JAG1
Application Note:
Flow Cytometry: (1:20-1:100). Optimal conditions should be determined individually for each application.
Background:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human Jagged-1.
NCBI Gene ID #:
182
NCBI Official Name:
jagged 1
NCBI Official Symbol:
JAG1
NCBI Organism:
homo sapiens
Physical State:
Liquid
Protein Accession #:
4557679
Protein GI Number:
NP_000205
Research Area:
Cancer
SPECIFICITY:
Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Swissprot #:
P78504
User NOte:
Optimal dilutions for each application to be determined by the researcher.