Further Information
Alternate Names/Synonyms:
BRN0072205; NSC147755; Coltramyl; 10-thio-Colchicoside; 2-Demethoxy-2-glucosidoxythiocolchicine
Light yellow to dark yellow powder.
602-41-5
32160000
liquid
GHS07
Keep cool and dry.Protect from light and moisture.
H302, H317, H335
InChI=1S/C27H33NO10S/c1-12(30)28-16-7-5-13-9-18(37-27-24(34)23(33)22(32)19(11-29)38-27)25(35-2)26(36-3)21(13)14-6-8-20(39-4)17(31)10-15(14)16/h6,8-10,16,19,22-24,27,29,32-34H,5,7,11H2,1-4H3,(H,28,30)/t16-,19+,22+,23-,24+,27+/m0/s1
LEQAKWQJCITZNK-AXHKHJLKSA-N
Chemical. CAS: 602-41-5. Formula: C27H33NO10S. MW: 563.6. Synthetic. Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Described to be a muscle relaxant. Anti-inflammatory agent with analgesic properties. Shown to be an anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products. Therapeutic option for the management of bone metastatic disease.
MFCD09026931
C27H33NO10S
563.6
Vial
P301, P312, P302, P352, P304, P340, P330
Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Described to be a muscle relaxant. Anti-inflammatory agent with analgesic properties. Shown to be an anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products. Therapeutic option for the management of bone metastatic disease.
>98% (HPLC)
Warning
COC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C2CC[C@H](NC(C)=O)C3=CC(=O)C(SC)=CC=C3C2=C1OC
Soluble in water (10 mg/ml).
Synthetic.
Non-hazardous
Biochemical Reagents
12352200
Stable for at least 2 years after receipt when stored at +4°C.