ProSci

CHRNA7 Antibody

Product Code:
 
PSI-43-140
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Porcine (pig)
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
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43-140 (5ug/ml) staining of paraffin embedded Rat Cerebral Cortex (A) and Rat Hippocampus (B), CRY-staining with DAPI nuclear counter stain in blue. Antigen retrieval with citrate buffer pH 6 at 95-98C.
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43-140 (5ug/ml) staining of paraffin embedded Rat Cerebral Cortex (A) and Rat Hippocampus (B), CRY-staining with DAPI nuclear counter stain in blue. Antigen retrieval with citrate buffer pH 6 at 95-98C.

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PSI-43-140-0.1mg0.1mg£626.00
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This product comes from: United States.
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Further Information

Additional Names:
CHRNA7, cholinergic receptor, nicotinic, alpha 7, NACHRA7, a7 nicotinic acetylcholine receptor, alpha 7 neuronal nicotinic acetylcholine receptor, alpha-7 nicotinic cholinergic receptor subunit, alpha7 nicotinic receptor subunit, cholinergic receptor, nicotinic, alpha polypeptide 7, neuronal acetylcholine receptor protein, alpha-7 chain, neuronal nicotinic acetylcholine receptor alpha-7 subunit, nicotinic acetylcholine alpha-7 subunit, nicotinic acetylcholine receptor alpha7 subunit, nicotinic cholinergic receptor alpha 7
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Immunohistochemistry:In paraffin embedded Rat Cerebral Cortex and Rat Hippocampus shows membranous staining in neural cells. Recommended concentration: 5-10ug/ml. Paraffin embedded Human Brain (Cortex). Recommended concentration: 3-6ug/ml.
Background References:
  • Ren K, King MA, Liu J, Siemann J, Altman M, Meyers C, Hughes JA, Meyer EMThe alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Dog, Cow
Immunogen:
The immunogen for this antibody is: KRPGEDKVRPACQHKQ
NCBI Gene ID #:
1139
NCBI Official Name:
cholinergic receptor, nicotinic, alpha 7 (neuronal)
NCBI Official Symbol:
CHRNA7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000737.1
Protein GI Number:
4502831
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer,Immunology,Signal Transduction,Cancer Immunology Signal Transduction Membrane Membrane
SPECIFICITY:
This antibody also reacts with CHRNA7-FAM7A fusion isoform 1 (NP_647536.1) and isoform 2 (NP_683709.1).
Swissprot #:
P36544