Further Information
Glra1, glycine receptor, alpha 1, GLYRA1, glycine receptor 48 kDa subunit, glycine receptor strychnine-binding subunit, glycine receptor subunit alpha-1, glycine receptor, alpha 1 subunit
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 60kDa band observed in Mouse and Rat Testis lysates (calculated MW of 51.7kDa according to Mouse NP_065238.2). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 0.3-1ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Lung and Kidney. Recommended concentration: 5ug/ml.
- Wang Q, Lynch JW.Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
The immunogen for this antibody is: CLQAKDGISVKGAN
2741
glycine receptor, alpha 1
Glra1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 60kDa
NP_037265.1
119372310
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Neuroscience,Signal Transduction,Neuroscience Signal Transduction Membrane Membrane
The immunizing peptide represents part of the cytoplasmic domain. The antibody is not expected to cross-react with other glycine receptor alpha proteins.
P23415