ProSci

ORL1 / LOX1 / LOXIN Antibody

Product Code:
 
PSI-43-707
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
1 / 1
43-707 (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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43-707 (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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PSI-43-707-0.1mg0.1mg£626.00
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This product comes from: United States.
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Further Information

Additional Names:
OLR1, oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, C-type lectin domain family 8 member A, OTTHUMP00000238950, OTTHUMP00000238954, OTTHUMP00000238955, OTTHUMP00000238958, hLOX-1, lectin-type oxidized LDL r
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 40kDa band observed in Human Liver lysates (calculated MW of 30.9kDa according to NP_002534.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Yoshida et al, Biochem J. 1998 Aug 15;334 (Pt 1):9-13. PMID: 9693095). Recommended concentration: 0.1-0.3ug/ml.
Background References:
  • Shi Y, Cosentino F, Camici GG, Akhmedov A, Vanhoutte PM, Tanner FC, L?scher TF.Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: DLKIQTVKDQPDEK-C
NCBI Gene ID #:
4973
NCBI Official Name:
oxidized low density lipoprotein (lectin-like) receptor 1
NCBI Official Symbol:
OLR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 40kDa
Protein Accession #:
NP_002534.1, NP_001166103.1, NP_001166104.1
Protein GI Number:
119616564
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction,Signal Transduction Membrane Membrane
SPECIFICITY:
This antibody is expected to recognize all reported isoforms (NP_002534.1; NP_001166103.1; NP_001166104.1).
Swissprot #:
P78380