ProSci

DYRK1A Antibody

Product Code:
 
PSI-43-184
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
1 / 1
43-184 (0.5ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.
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43-184 (0.5ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

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PSI-43-184-0.1mg0.1mg£626.00
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Further Information

Additional Names:
DYRK1A, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, DYRK, DYRK1, HP86, MNB, MNBH, MRD7, MNB/DYRK protein kinase, OTTHUMP00000109090, OTTHUMP00000109091, OTTHUMP00000109094, OTTHUMP00000174799, dual specificity YAK1-related kinase, dual specificity tyrosine-phosphorylation-regulated kinase 1A, hMNB, mnb protein kinase homolog hp86, protein kinase minibrain homolog, serine/threonine kinase MNB, serine/threonine-specific protein kinase
Application Note:
Peptide ELISA: antibody detection limit dilution 1:64000.Western Blot:Approx 80kDa band observed in lysates of cell line K562 (calculated MW of 85.6kDa according to NP_001387.2). Recommended concentration: 0.5-2ug/ml. Primary incubation was 1 hour.Immunoprecipitation: This product has been successfully used in IP on Human: Widowati et al, BMC Res Notes.?2018 May 15;11(1):297.?PMID: 29764512.
Background References:
  • Miyata Y, Nishida E.DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: PHSHQYSDRRQPN-C
NCBI Gene ID #:
1859
NCBI Official Name:
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
NCBI Official Symbol:
DYRK1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 80kDa
Protein Accession #:
NP_001387.2, NP_569120.1, NP_567824.1, NP_569122.1
Protein GI Number:
18765758
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience,Neuroscience
SPECIFICITY:
This antibody is expected to recognize all reported isoforms (NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1). This antibody is not expected to cross-react with DYRK1B.
Swissprot #:
Q13627