ProSci

CD105 Antibody [MJ7/18] (PE)

Product Code:
 
PSI-76-828
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MJ7/18
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-828-0.1mg0.1mg£505.00
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Further Information

Additional Names:
Endo, CD105, AI528660, AI662476, S-endoglin, Eng
Background:
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.
Background References:
  • Ge, A. Z., Butcher, E. C. (1994). Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF--beta- ligand.Gene,138(1), 201-206.
  • Onoe, T., Ohdan, H., Tokita, D., Shishida, M., Tanaka, Y., Hara, H., ... Asahara, T. (2005). Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice.The Journal of Immunology,175(1), 139-146.
  • St-Jacques, S., Cymerman, U. R. S. Z. U. L. A., Pece, N. A. D. I. A., Letarte, M. (1994). Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells.Endocrinology,134(6), 2645-2657.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
13805
NCBI Official Name:
endoglin
NCBI Official Symbol:
Eng
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Stem Cell
SPECIFICITY:
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells.
Swissprot #:
Q63961
User NOte:
Optimal dilutions for each application to be determined by the researcher.