ProSci

Foxp3 Antibody [MF23] (APC)

Product Code:
 
PSI-77-169
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MF23
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
PSI-77-169-0.1mg0.1mg£662.00
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Further Information

Additional Names:
sf, JM2, scurfin, Foxp3
Background:
The MF23 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression. Mutations of Foxp3 result in the ?scurfy? mice phenotype. It is reported that the MF23 antibody recognizes an epitope between 1-87 amino acids in the N-terminal domain of mouse Foxp3.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
20371
NCBI Official Name:
forkhead box P3
NCBI Official Symbol:
Foxp3
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The MF23 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors.
Swissprot #:
Q99JB6
User NOte:
Optimal dilutions for each application to be determined by the researcher.