ProSci

CD44 (phospho Ser706) Antibody

Product Code:
 
PSI-79-963
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) Antibody. The lane on the right is treated with the antigen-specific peptide.

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PSI-79-963-0.1mg0.1mg£488.00
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Further Information

Additional Names:
CD44 antigen precursor, ECMR-III, Epican, Hermes antigen, PGP-1
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Background References:
  • Ildefonso CJ, et al. (2012)J Biol Chem 287, 32697-707. Pivetta E, et al. (2011)J Cell Physiol 226, 769-79. Wang YT, et al. (2010)J Proteome Res 9, 5582-97.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CD44 (phospho Ser706) antibody was raised against a peptide sequence around phosphorylation site of serine 706 (S-K-S (p)-Q-E) derived from Human CD44.
Modifications:
Phospho-Specific
NCBI Gene ID #:
960
NCBI Official Name:
CD44 molecule (Indian blood group)
NCBI Official Symbol:
CD44
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81, 90, kDa
Protein Accession #:
NP_000601.3
Protein GI Number:
48255935
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of CD44 only when phosphorylated at serine 706.
Swissprot #:
P16070