ProSci

IL-20 Receptor 2 Antibody [20RNTC]

Product Code:
 
PSI-76-001
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
20RNTC
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Immunocytochemistry (ICC)
  • Western Blot (WB)
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
PSI-76-001-0.1mg0.1mg£560.00
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Further Information

Additional Names:
DIRS1, FNDC6, IL-20R2, Fndc6, Gm186, Il20R2, AV228068, IL20RB
Background:
The 20RNTC monoclonal antibody specifically reacts with human and mouse interleukin-20 receptor 2 (IL-20R2 or IL-20Rb). IL-20R2 is a class II cytokine receptor that pairs with IL-20R to form a receptor capable of binding IL-19, IL-20, or IL-24 and binds IL-20, or IL-24 when paired with IL-22R1. It is primarily found on epithelial originated cells such as those found in the skin or intestines.
Background References:
  • Blumberg, H., Conklin, D., Xu, W., Grossmann, A., Brender, T., Carollo, S., ... Chandrasekher, Y. A. (2001). Interleukin 20: discovery, receptor identification, and role in epidermal function.Cell,104(1), 9-19.
  • Wahl, C., M, W., Leith, F., Adler, G., Oswald, F., Reimann, J., ... Wegenka, U. M. (2009). IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses.The Journal of Immunology,182(2), 802-810.
  • Dumoutier, L., Leemans, C., Lejeune, D., Kotenko, S. V., Renauld, J. C. (2001). Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.The Journal of Immunology,167(7), 3545-3549.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
53833; 213208
NCBI Official Name:
interleukin 20 receptor beta
NCBI Official Symbol:
IL20RB
NCBI Organism:
Homo sapiens; Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The 20RNTC monoclonal antibody specifically reacts with human and mouse interleukin-20 receptor 2 (IL-20R2 or IL-20Rb).
Swissprot #:
Q6UXL0
User NOte:
Optimal dilutions for each application to be determined by the researcher.