ProSci

CD193 Antibody [5E8-G9-B4] (PE)

Product Code:
 
PSI-76-859
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
5E8-G9-B4
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-859-100tests100tests£433.00
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Further Information

Additional Names:
CKR3, CD193, CMKBR3, CC-CKR-3, CCR3
Background:
The 5E8-G9-B4 monoclonal antibody specifically reacts with human CD193, also known as CKR3 and CCR3. CD193. CD193 is a G protein-coupled seven transmembrane receptor that binds to eotaxin-1,2,3 and to a lesser degree to MCP-3,4 and RANTES. It is expressed on eosinophils and basophils, mast cells platelets, CD34+ hematopoietic progenitor, and mononuclear phagocytes. CD193 plays a role in asthma and is a co-receptor for HIV-1,2.
Background References:
  • Breviario, F., Caveda, L., Corada, M., Martin-Padura, I., Navarro, P., Golay, J., ... Dejana, E. (1995). Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. Arteriosclerosis, thrombosis, and vascular biology,15(8), 1229-1239.
  • Rajesh, D., Chinnasamy, N., Mitalipov, S. M., Wolf, D. P., Slukvin, I., Thomson, J. A., Shaaban, A. F. (2007). Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.Stem Cells,25(2), 490-499.
  • Dejana, E., Bazzoni, G., Lampugnani, M. G. (1999). Vascular endothelial (VE)-cadherin: only an intercellular glue.Experimental cell research,252(1), 13-19.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
1232
NCBI Official Name:
chemokine (C-C motif) receptor 3
NCBI Official Symbol:
CCR3
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Stem Cell,Chemokines & Cytokines, Growth Factors
SPECIFICITY:
The 5E8-G9-B4 monoclonal antibody specifically reacts with human CD193, also known as CKR3 and CCR3.
Swissprot #:
P51677
User NOte:
Optimal dilutions for each application to be determined by the researcher.