ProSci

CD1a Antibody [HI149] (FITC)

Product Code:
 
PSI-76-084
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
HI149
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-084-25tests25tests£312.00
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Further Information

Additional Names:
R4, T6, CD1, FCB6, HTA1, CD1A
Background:
The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein. It is expressed on dendritic cells, Langerhans cells, and cortical thymocytes. CD1a plays a role in antigen presentation and ,like MHC Class I, it non-covalently associates with Beta2-microglobulin.
Background References:
  • Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
  • Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
  • Hanau, D., Schmitt, D. A., Bieber, T., Schmitt, D., Cazenave, J. P. (1990). Possible mechanism of action of CD1a antigens.Journal of investigative dermatology,95(5), 503-505.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
909
NCBI Official Name:
CD1a molecule
NCBI Official Symbol:
CD1A
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity,Immunology
SPECIFICITY:
The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein.
Swissprot #:
P06126
User NOte:
Optimal dilutions for each application to be determined by the researcher.