ProSci

IL-10 Recombinant Protein

Product Code:
 
PSI-40-417
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
The lyophilized IL-10 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
 

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CodeSizePrice
PSI-40-417-0.002mg0.002mg£300.00
Quantity:
PSI-40-417-0.01mg0.01mg£428.00
Quantity:
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Further Information

Additional Names:
CSIF, Il-10, Interleukin-10, Cytokine synthesis inhibitory factor, IL-10
Background:
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.
Biological Activity:
Murine IL - 10 is fully biologically active as measured by the dose - dependent co - stimulation (with IL - 4) of the proliferation of murine MC/9 cells. The ED50 was found to be < 2 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
NCBI Gene ID #:
16153
NCBI Official Name:
interleukin 10
NCBI Official Symbol:
Il10
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_034678.1
Protein GI Number:
6754318
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P18893

Documents