ProSci

LIGHT Recombinant Protein

Product Code:
 
PSI-40-301
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
 

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CodeSizePrice
PSI-40-301-0.003mg0.003mg£300.00
Quantity:
PSI-40-301-0.015mg0.015mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
LTg, TR2, CD258, HVEML, LIGHT, UNQ391/PRO726, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L
Background:
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.
NCBI Gene ID #:
8740
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 14
NCBI Official Symbol:
TNFSF14
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_003798.2
Protein GI Number:
25952144
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
High-5 Insect cells
Swissprot #:
O43557

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