ProSci

APRIL Recombinant Protein

Product Code:
 
PSI-40-302
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized APRIL recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted APRIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-40-302-0.002mg0.002mg£300.00
Quantity:
PSI-40-302-0.01mg0.01mg£428.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
APRIL, CD256, TALL2, ZTNF2, TALL-2, TRDL-1, UNQ383/PRO715, APRIL, Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand
Background:
APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.
Biological Activity:
Determined by its ability to induce NF-κB activation in HEK293-NF-κB reporter cells transfected with BCMA receptor.
NCBI Gene ID #:
8741
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 13
NCBI Official Symbol:
TNFSF13
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001185551.1
Protein GI Number:
310750385
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
High-5 Insect cells
Swissprot #:
O75888

Documents