ProSci

TNF beta Recombinant Protein

Product Code:
 
PSI-40-275
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized TNF beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TNF beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein,
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-40-275-0.005mg0.005mg£300.00
Quantity:
PSI-40-275-0.02mg0.02mg£428.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
LT, TNFB, TNFSF1, Lymphotoxin-alpha, TNF-beta, LT-alpha
Background:
TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-α, TNF-β is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant human TNF-β is a secreted 171 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution.
Biological Activity:
The ED50 was determined by the cytolysis of murine L929 cells in the presence of Actinomycin - D is ≤ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 x 107 units/mg.
NCBI Gene ID #:
4049
NCBI Official Name:
lymphotoxin alpha
NCBI Official Symbol:
LTA
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000586.2
Protein GI Number:
6806893
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P01374

Documents