ProSci

BDNF Recombinant Protein

Product Code:
 
PSI-40-496
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized BDNF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BDNF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
 

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CodeSizePrice
PSI-40-496-0.002mg0.002mg£300.00
Quantity:
PSI-40-496-0.01mg0.01mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
ANON2, BULN2, Brain-derived neurotrophic factor, Abrineurin, BDNF
Background:
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.
Biological Activity:
Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.
NCBI Gene ID #:
627
NCBI Official Name:
brain-derived neurotrophic factor
NCBI Official Symbol:
BDNF
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001137277.1
Protein GI Number:
219842288
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P23560

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