ProSci

Activin A Recombinant Protein

Product Code:
 
PSI-40-213
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized Activin A recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Activin A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protei
 

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CodeSizePrice
PSI-40-213-0.002mg0.002mg£300.00
Quantity:
PSI-40-213-0.01mg0.01mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, Mothers against decapentaplegic homolog 2, MAD homolog 2
Background:
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Biological Activity:
The ED50 was determined by its ability to inhibit the proliferation of murine MPC - 11 cells is ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 105 units/mg.
NCBI Gene ID #:
4087
NCBI Official Name:
SMAD family member 2
NCBI Official Symbol:
SMAD2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001003652.1
Protein GI Number:
51173730
Purity:
Greater than 97% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q15796

Documents