ProSci

IP-10 Antibody

Product Code:
 
PSI-XP-5203Bt
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
IP-10 antibody is stable for at least 2 years from date of receipt at -20˚C. The reconstituted antibody is stable for at least two weeks at 2-8˚C. Frozen aliquots are stable for at least 6 months when stored at -20˚C. Avoid repeated freeze-
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To detect hIP-10 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.25 ? 1.0 ug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with ProSci?s Polyclonal Anti-Human IP-10 (XP-5203) as a capture antibody, allows the detection of at least 0.2 ? 0.4 ng/well of recombinant hIP-10.
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To detect hIP-10 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.25 ? 1.0 ug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with ProSci?s Polyclonal Anti-Human IP-10 (XP-5203) as a capture antibody, allows the detection of at least 0.2 ? 0.4 ng/well of recombinant hIP-10.

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CodeSizePrice
PSI-XP-5203Bt-0.05mg0.05mg£524.00
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This product comes from: United States.
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Further Information

Additional Names:
C7, IFI10, INP10, IP-10, crg-2, mob-1, SCYB10, gIP-10, C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10
Application Note:
ELISA:

Sandwich:
To detect hIP-10 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25 - 1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with our Polyclonal Anti-Human IP-10 (XP-5203) as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIP-10.

Western Blot:

To detect hIP-10 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIP-10 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Background:
Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.
Concentration:
batch dependent
Conjugate:
Biotin
Immunogen:
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIP-10 (human IP-10).
NCBI Gene ID #:
3627
NCBI Official Name:
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol:
CXCL10
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P02778
Protein GI Number:
21542456
Purification:
Anti-hIP-10 specific antibody was purified by affinity chromatography and then biotinylated.
Research Area:
Chemokines & Cytokines,Antibody Pairs
Swissprot #:
P02778
User NOte:
Centrifuge vial prior to opening.