ProSci

STK3 Antibody

Product Code:
 
PSI-30-436
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store STK3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 4
Antibody used in IHC on Human kidney at 4.0-8.0 ug/ml.
2 / 4
3 / 4
4 / 4
Antibody used in WB on Human RPE-1 at: 1:2000 (Lane1: 100ug uninduced RPE-1 lysate, Lane2: 100ug uninduced RPE-1 lysate, Lane3: 100ug STK3 induced RPE-1 lysate, Lane4: 100ug STK3 induced RPE-1 lysate).

Antibody used in IHC on Human kidney at 4.0-8.0 ug/ml.
Antibody used in WB on Human RPE-1 at: 1:2000 (Lane1: 100ug uninduced RPE-1 lysate, Lane2: 100ug uninduced RPE-1 lysate, Lane3: 100ug STK3 induced RPE-1 lysate, Lane4: 100ug STK3 induced RPE-1 lysate).

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PSI-30-436-100ul100ul£609.00
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Further Information

Additional Names:
STK3, FLJ90748, KRS1, MST2
Application Note:
STK3 antibody can be used for detection of STK3 by ELISA at 1:312500. STK3 antibody can be used for detection of STK3 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand.Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-11 U26424.1 1-11 12-2826 BC010640.2 1-2815
Background References:
  • Seidel, C., (2007) Mol. Carcinog. 46 (10), 865-871.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STK3.
NCBI Gene ID #:
6788
NCBI Official Name:
serine/threonine kinase 3
NCBI Official Symbol:
STK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
NP_006272
Protein GI Number:
103471999
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Cancer ,Signal Transduction ,Immunology ,Apoptosis
Swissprot #:
Q13188
User NOte:
Optimal dilutions for each application to be determined by the researcher.